Next-Gen Toxicology: Inside the Organ Chip Revolution with Dr. Donald Ingber

In this episode of ToxChats, hosts Lauren Walker and Sarah Benjamin sit down with the groundbreaking Donald Ingber—visionary scientist, engineer, and Founding Director of the Wyss Institute. Dr. Ingber shares how his unique path through medicine, biology, and design converged to spark breakthroughs such as human Organ Chips—systems that are redefining toxicology, drug development, and disease modeling. Together, they discuss how Organ Chips outperform traditional in vitro and animal models, the promise of personalized “human avatars,” and the technical, regulatory, and cultural challenges that remain. Future-focused and packed with insight, this episode spotlights the breakthroughs changing toxicology as we know it.